Abstract
Phrenic nerve electrical activity was recorded and integrated in 14 dogs during hypercapnia without hypoxia and during hypoxia without hypercapnia. The dogs were anesthetized with intravenous pentobarbital or chloralose. In dogs anesthetized with cither agent, hypercapnia primarily augmented the electrical activity of each phrenic nerve burst, while hypoxia increased burst frequency more than integrated phrenic nerve burst activity. Heart rate slowed during both hypoxia and hypercapnia. There was a small rise in systemic blood pressure with hypoxia but not with hypercapnia. When both arterial carbon dioxide and oxygen tension were kept constant, large, but not small, increases in systemic blood pressure decreased burst electrical activity. Hypoxia and hypercapnia may act on different subunits of the respiratory center.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
