Abstract
We report on a multi-sensor system for the parallel in-situ monitoring of cell nutrients, metabolites and cell mass in biotechnological processes. The integration of enzyme sensors and impedance spectroscopy on one chip for applications in bioreactors is demonstrated for the first time to our best knowledge. Measurements of glucose and lactate concentrations in a wide range are shown with linear ranges up to 600 mM and 900 mM, respectively. The glucose and cell mass sensor in parallel are successfully employed in a cell culture of Saccharomyces cerevisiae to monitor glucose consumption and increasing mass of the cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
