Abstract
The contribution of naturally derived products for drug discovery purposes is undisputed. The implementation of high-throughput screening (HTS) technologies has allowed the rapid and effective investigation of the chemical composition and pharmacological properties of a large number of plant extracts against several biological targets. The scope of this study was the discovery of plant derived tyrosinase inhibitors utilizing a HTS approach and the introduction of an integrated methodology for the rapid identification of bioactive compounds during bioassay-guided procedures.
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