Abstract
The conceptual and theoretical framework for a modular integrated Exposure and Dose Modeling and Analysis System (EDMAS) has been formulated, and its stepwise implementation and testing is currently in progress. This system aims to provide state-of-the-art tools for performing integrated assessments of exposure and dose for individuals and populations. The integration of modeling components with each other as well as with available environmental, exposure, and toxicological databases is being ac complished with the use of computational tools that include interactive simulation environments, Geographical Informa tion Systems, and various data retrieval, management, statistical analysis, and visualization methods. This paper overviews the structure and modular nature of this integrated modeling system and focuses specifically on two of its components: (a) a hierarchy of physiologically based pharmacokinetic models (PBPKM), representing various levels of detail and sophistication, and (b) a family of microe...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
