Integrated backscatter of hypertensive retinopathy by ultrasonic tissue characterization

Abstract

Objective To investigate the integrated backscatter(IBS) changes of retina in hypertensive disease patients to offer the reference to clinician for ocular fundus changes of hypertensive disease. Methods One hundred chronic hypertension patients (100 eyes) were divided into 4 groups by clinical stages: ① gradeⅠ, 28 persons (28 eyes); ② grade Ⅱ, 27 persons (27 eyes); ③ grade Ⅲ, 24 persons (24 eyes); ④ grade Ⅳ, 21 persons (21 eyes). Thirty normal persons of 30 eyes were the control group. Their IBS values were measured on nose side of retina, and the correction IBS values(IBS%) were calculated. Results With the deterioration of hypertensive disease, the IBS(29.48±0.09, 32.50±0.04, 34.62±0.39, 36.48±0.46, 37.52±0.43) and IBS%[(68.50±2.11)%, (72.03±0.57)%, (74.29±0.77)%, (76.06±1.43)%, (77.45±0.75)%] of retina were gradually increased. The statistical difference were found among various groups(P=0.000). Conclusions With the deterioration of hypertensive retinopathy, the IBS and IBS% increased gradually. The IBS technique is a useful method to assess the retinopathy of hypertension. Key words: Ultrasonography; Hypertensive retinopathy; Integrated backscatter