Abstract

The flow velocity profiles and particles concentration profiles in a flow are often required for design and optimal operation of various flow-exploiting biomedical instruments. A new optical probing technique named Integral Doppler Anemometry (IDA) allows the fast and precise measurements of these profiles in narrow channels with the optically transparent walls and characteristic width from tens of microns up to several millimeters. The shape of IDA spectrum is determined by the flow velocity profile and the concentrational profile of light scattering particles in a flow. These profiles can be reconstructed from the measured spectrum by means of special measuring and data processing procedures. The basic principles of IDA technique and the main requirements to IDA measurements are formulated. The analytical expressions giving the shape of IDA spectrum for the practically used optical arrangement of anemometer are presented. The algorithms of reconstruction of flow velocity and particles concentration profiles from IDA spectra are discussed. Measurements showed an essentially nonuniform lateral distribution of erythrocytes in a flow in such channels, namely, the transverse hydrodynamic focusing of cells.

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