Abstract
Pharmacology, Toxicology and Biomedical Reports,2019,5,2,65-68.DOI:10.5530/PTB.2019.5.11Published:July 2019Type:Review ArticleAuthors:Yousef Ahmed Alomi, Mohammed Abdulaziz Altuwaijri, Mohsen Huraybie Alshammari, and Nouf Hameed Al-Muallad Author(s) affiliations:Yousef Ahmed Alomi*, General Administration of Pharmaceutical Care, Ministry of Health, Riyadh, SAUDI ARABIA. Mohammed Abdulaziz Altuwaijri, ENT Consultant, King Saud Medical City, Riyadh, SAUDI ARABIA. Mohsen Huraybie Alshammari, Hail Maternaty and Childern Hospital, Ministry of Health, Hail, SAUDI ARABIA. Nouf Hameed Al-Muallad, Ibn Sina College Hospital, Jeddah, SAUDI ARABIA. Abstract:Objectives: To review the intake of antibiotics and fasting during the holy month of Ramadan. Methods: In this study, we performed an extensive search of 50 databases following the Saudi Digital Library search engine. We included meta-analysis, randomized controlled studies and observational studies published in English language with human study only for update May 2017. The search terms included Ramadan, fasting, medication, therapy, type of disease and medication based on therapeutic class. The list of antibiotic medication and switch from regular days to Ramadan days based on literature search revealed comparative safety studies, efficacy studies and cost of type of medication for each disease studies and national or international evidence-based guidelines of switching short half-life to long halflife. All parenteral dosage form of medication were excluded from study. All medications should be listed in the Ministry of Health drug formulary. Results: A total of 710 studies were obtained after an extensive search with specific terms. Of those, 104 studies were duplicate studies and 606 were considered for further evaluation. After evaluation, we obtained 30 studies which discussed about the antibiotics and Ramadan. Of these 30 studies, only 2 studies were found to be appropriate for further revision. Among the two, one study was an observational study regarding the pattern of prescribing antibiotics during the holy month of Ramadan. The second study was about the systemic review on the safety of fasting and several infectious diseases. The suggested draft of list of antibiotic switch from regular days to the holy Ramadan days was explored in this review. Conclusion: The investigations about antibiotics intake during fasting not found. The studies of antibiotic during the holy month of Ramadan is required during legal registrations at all Muslim countries. Antibiotics switch therapy during fasting is highly recommended at all Muslim patients in the world. Keywords:Antibiotics, Fasting, Literature, Ramadan, ReviewView:PDF (190.51 KB) PDF PDF Images Table 1: The antibiotic studies conducted during the holy month of Ramadan.
Highlights
The General Administration of Pharmaceutical Care founded the National Stewardship of Antimicrobial Program in 2014 at the Ministry of Health (MOH) hospitals in the Kingdom of Saudi Arabia.[1,2] The project was established through the pharmacy strategic planning task force committee
Of the 606 studies, 92 studies discussed about medications related to diabetes mellitus and Ramadan, 27 studies discussed about the psychiatry and Ramadan, 27 studies investigated gastrointestinal diseases and Ramadan, 30 studies discussed about the intake of antibiotics and Ramadan, 30 studies discussed about the cardiovascular diseases and Ramadan, 15 studies discussed about medicines for asthma, rheumatoid arthritis and Ramadan and 402 studies discussed about other diseases and Ramadan
The suggested draft of antibiotics list switching from regular days to the holy Ramadan days (Table 2)
Summary
The General Administration of Pharmaceutical Care founded the National Stewardship of Antimicrobial Program in 2014 at the MOH hospitals in the Kingdom of Saudi Arabia.[1,2] The project was established through the pharmacy strategic planning task force committee. The antibiotic guidelines consisted of disease management and names of all available medications in the MOH drug formulary, the dosing frequency and time of administration. These guidelines are applicable during all months of the year. During the holy month Ramadan, it changes. In this month, all Muslims should perforce fast. The fast starts from sunrise and followed until sunsets. During this period, the patient should stop taking any medications. The review, did not mention how to administer the medications during the holy month of Ramadan. In this study, we aimed to explore the intake of antibiotics and the time administration during the Ramadan fasting
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