Abstract
Intake-excretion studies of fat and nitrogen were performed in 7 patients with Wilson's disease. Standard technics were used. Fecal fat excretion was slightly to moderately increased in 2 patients who had Wilson's disease with clinically overt cirrhosis (average daily fecal fat excretion up to 16.5 gm. and 9.5 gm., respectively). Fecal fat values reverted to normal in these 2 patients as clinical improvement occurred. Fecal nitrogen excretion was normal for all 7 patients with Wilson's disease. The pathogenetic basis for steatorrhea in Wilson's disease has not been established.
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