Intact kidney’s functional changes in course of the acute unilateral kidney inflammation in rats: different time frames after nephrectomy on the affected side

О С Федорук ,М С Степанченко

doi:10.24061/2413-0737.xix.1.73.2015.45

Abstract

An affected kidney was removed in various terms of the experiment in order to determine its influence on functional activity of the intact kidney. Nephrectomy on the affected side was performed on the 10th, 14th and 21st days. Functional scores of the residual kidney were evaluated 4, 7 and 14 days after nephrectomy. Control group constituted animals without nephrectomy. Scores were compared to the respective ones of the intact kidney in control group, on the same day of experiment. Reliable changes of almost all functional kidney scores were detected after removal of the affected organ. Early nephrectomy (on the10th and 14th days) evoked compensatory reaction of the residual kidney and resulted in normalization of functional parameters on the 28th day.

Highlights

By the examples of clinical cases, the paper shows the advisability of using pericardioscopy in complex of detecting tumoral pericarditis, its effectiveness relative to verification of tumor nature, and performing variety of palliative surgical procedures, which improve the quality of patients life
4 clinical cases are presented which prove the effectiveness of pericardioscopy as diagnostic, curative and palliative surgical procedures for oncologic lesion
Перспективним є подальше дослідження гістопатологічних та мікробіологічних змін тканин контрлатеральної нирки в різні терміни після видалення ураженого органа за гострого однобічного запального процесу нирок у щурів

Summary

Introduction

By the examples of clinical cases, the paper shows the advisability of using pericardioscopy in complex of detecting tumoral pericarditis, its effectiveness relative to verification of tumor nature, and performing variety of palliative surgical procedures, which improve the quality of patients life. Функціональні показники резидуальної нирки досліджували через 4, 7 та 14 діб від нефректомії. Показники порівнювали з аналогічними в інтактної нирки на таку ж добу експерименту у щурів, що не піддалися нефректомії з ураженого боку.

Results

Conclusion