Abstract
The insulin-like growth factors (IGFs) play essential roles in growth and development. A large body of experimental evidence has been accumulated that clearly indicates their importance in fetal growth and organogenesis, as well as their important roles in postnatal growth and in the specific function of various organ systems, including the immune, reproductive, nervous, and musculoskeletal systems 1, 2). Though the IGFs were originally considered to function as endocrine mediators, their expression in most tissues of the body suggests that both paracrine and autocrine mechanisms are equally important in IGF action at the cellular level (3, 4).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.