Abstract
AbstractThe sections in this article are:Indirect Evidence that Insulin‐Like Growth Factor I Participates in the Regulation of Somatic GrowthClinical: Correlations Between Growth and Insulin‐Like Growth Factor I Levels in SerumExperimental: Growth Hormone‐Dependent Regulation of Insulin‐Like Growth Factor ImRNAand Protein Expression in Various Tissues and the Autocrine/Paracrine Versus Endocrine Role of Insulin‐Like Growth Factor IDirect Evidence that Insulin‐Like Growth Factor I Promotes GrowthInsulin‐Like Growth Factor I as a Growth and Differentiation Factor In VitroEffects of Insulin‐Like Growth Factor I Administration on Growth In VivoTransgenic Animals Overexpressing Growth Hormone or Insulin‐Like Growth Factor IInsulin‐Like Growth Factor I and Type 1 Insulin‐Like Growth Factor Receptor Knock‐Out AnimalsThe Somatomedin Hypothesis Revisited
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