Abstract

A complex of methods for the in-vitro and in-vivo bone analysis was developed. Among the in-vitro methods are: INAA with reactor and 14 MeV neutrons; IGAA with 25 MeV linear accelerator; XRF with55Fe,109Cd,241Am radionuclide sources. Twenty-five elements could be analyzed by it: N, F, Na, Mg, P, Cl, K, Ca, Sc, Cr, Mn, Fe, Co, Zn, Se, Br, Rb, Sr, Ag, Sb, Cs, Ba, Tb, Hg, and Pb. Among the in-vivo methods are: INAA of band, foot and spine Ca and limb bone tumour Ca, Na and Cl with238Pu−Be neutron sources; IGAA of N and P in limb bone tumours; XRF of tooth Ca, Zn, Sr and Pb with109Cs radionuclide sources. The methods developed were used both in clinical and experimental medicine for studying the healthy human and animal bone with different diseases and environmental influence.

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