Inspection of Solid Dosage Forms using THz Imaging Spectroscopy

Abstract

Abstract The present work describes a laboratory terahertz (THz) imaging spectroscopy system and its possibilities to inspect solid dosage forms in the form of coated tablets and capsules. Moreover, the chemical composition and layer structure of coated pharmaceutical tablets are investigated. These chemical and physical properties of solid dosage forms can be used for the detection of counterfeit drugs. Preliminary results show that THz time domain spectroscopy and imaging is a promising technology for contactless control and analysis of pharmaceutical drug materials and final dosage forms.