Inspection of Intraocular Lens With Dual-Side View Optical Coherence Tomography

Qian Wu,Linbo Liu,Jianhua Mo,Xiwen Wang

doi:10.1109/jphot.2021.3080498

Qian Wu, Linbo Liu + Show 2 more

Open Access

https://doi.org/10.1109/jphot.2021.3080498

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Abstract

Intraocular lens (IOL) is widely used for cataract treatment. Its optical properties are crucial to obtain a good treatment efficacy and thus need to be evaluated and controlled. In this study, we propose a novel method based on optical coherence tomography (OCT) for noncontact and accurate <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">in vitro</i> measurement of thickness, refractive index and dioptric power of IOL implants. The OCT setup is specially designed to create two sampling optics, called dual-side view OCT (DSV-OCT), which allows for imaging IOL from the two opposite sides simultaneously in single OCT volume scanning. This can produce a three-dimensional surface contour without suffering image distortions due to the refraction of the curved surface. Then, the thickness and surface curvature can be easily computed from the surface contours. In addition, DSV-OCT is able to measure the refractive index. Three IOLs with different dioptric powers (5D, 20D and 28D) were chosen to evaluate this method. The results show that this method is capable to provide a comprehensive and accurate evaluation of IOLs from the aspects of thickness, refractive index and dioptric power, and hence can be potentially used as a quality assurance tool by IOL manufacturers.

Highlights

IntroductionMore than 65.2 million people worldwide have cataracts according to the first world report on vision issued by the World Health Organization in 2019 [1]
Cataract is one of the common eye diseases in the aging population
We propose to employ dual-side view optical coherence tomography (DSV-OCT) as a single-shot solution for thickness, refractive index and dioptric power measurements of intraocular lens (IOL)

Summary

Introduction

More than 65.2 million people worldwide have cataracts according to the first world report on vision issued by the World Health Organization in 2019 [1]. Given that cataracts get worse over time, people left untreated will experience increasingly severe vision impairment which can lead to blindness. The common treatment for cataract is the replacement of the natural lens by an intraocular lens (IOL). IOL implantation in refractive cataract surgery has become one of the most commonly performed surgical operations in medicine since the first implantation of IOLs [2]. Most of the cataract post-surgical device-associated complications are directly related to some fundamental IOL optical properties such as dioptric power, imaging quality, refractive index (RI), thickness, and geometrical shape [3]. Effective and accurate measurement on IOL optical properties before IOL implantation is highly desired in order to reduce IOL complications

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