Inside Cover: Radical Acylfluoroalkylation of Olefins through N‐Heterocyclic Carbene Organocatalysis (Angew. Chem. Int. Ed. 5/2020)

Abstract

The multicomponent acylfluoroalkylation of olefins through N-heterocyclic carbene (NHC) organocatalysis is presented by J.-L. Li, B. Han, Q.-Z. Li and co-workers in their Research Article page 1863. A broad spectrum of olefins, including styrenes, cyclic alkenes, indoles, vinyl ethers, vinyl esters, and unactivated alkenes, are compatible with this system. The generality of this method is further highlighted by the late-stage modification of pharmaceutical skeletons.