Abstract
Fluorescent Probes The synthesis and photophysics of a family of BODIPY derivatives with a naphthyridine at the C8 position and alkyl, bromo, or dimethylaminoaryl groups at the C2 and C6 positions of the BODIPY core are described by Tia E. Keyes and co-workers in their Full Paper on page 763 ff. The NIR emission of the dimethylaminoaryl compounds is Stokes-shifted and strongly solvent dependent. The emission and Stokes shift are maintained in aqueous media. PEGylation of these compounds renders them water soluble and cell permeable. Their Stokes-shifted fluorescence makes them less prone to self-quenching within live cells than conventional BODIPY fluorophores.
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