Abstract
A model for analyzing and predicting reaction rates is presented by F. M. Bickelhaupt and K. N. Houk in their Review on page 10070 ff. This model is based on dissecting reaction profiles and energy barrier heights in terms of reactant properties, in particular, the strain associated with distorting the reactants and the interaction between the distorted reactants. The model is illustrated with examples from organic and inorganic chemistry.
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