Abstract

Perioperative monitoring of blood coagulation is critical to guide hemostatic therapies and predict the risk of bleeding during surgical procedures. Up to now, point-of-care coagulation monitoring devices still do not fully meet the clinical practice. In article number 20200183, Yi Xu, Zhigang Wu and their co-workers provide an overview of design principles of microfluidic systems and their micro/nano fabrication strategies in studying the platelet adhesion and aggregation. The importance, benefits and challenges of introduced principles and methods are critically discussed to guide designing more versatile point-of-care (POC) devices for hemostasis monitoring and thrombosis diagnosis.

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