Insertion of arynes into the carbon–oxygen double bond of amides and its application into the sequential reactions

Eito Yoshioka,Hideto Miyabe

doi:10.1016/j.tet.2011.10.072

Insertion of arynes into the carbon–oxygen double bond of amides and its application into the sequential reactions

Eito Yoshioka, Hideto Miyabe

https://doi.org/10.1016/j.tet.2011.10.072

Copy DOI

Journal: Tetrahedron	Publication Date: Oct 28, 2011
Citations: 55

Affiliation: Hyogo University of Health Sciences

#Insertion Of Arynes #Reaction Of Arynes + Show 8 more

Abstract
Full-Text
Similar Papers

Abstract

The reaction of arynes, generated from ortho-(trimethylsilyl)aryl triflates, with the CO bond of formamides gave salicylaldehyde derivatives via the formation of formal [2+2] adducts. The sequential transformation of arynes into ortho-disubstituted arenes, o-aminoalkylphenols or o-hydroxyalkylphenols, was achieved by one-pot procedure using dialkylzincs.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title

Journal

Date

Author

View more papers

More From: Tetrahedron

Paper Title

Journal

Date

Author

View more papers

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.