Abstract
Modern methods of veterinary disinsection are based on the use of chemical agents. Efficiency of insecticides is determined by composition, form and method of use. Use of mixtures of insecticidal active substances is recommended as one of the anti-resistance strategies, with the most preferred formulations in the form of baits. The purpose of the present work was to evaluate the insecticidal efficacy of the bait composition containing ivermectin and fipronil against the adult fly of Musca domestica L. Intestinal insecticidal effect of a mixture of two active substances (ivermectin and fipronil) on the imago of M. domestica laboratory culture was evaluated by the method of group feeding in laboratory conditions. A mixture containing 0.06% ivermectin and 0.015% fipronil caused the death of (97.6 ± 2.4)% of insects during 24 hours of exposure. Developed insecticidal bait Mukhnet IF (ivermectin 0.06% + fipronil 0.015%) had a 100% insecticidal effect against imago M. domestica in the laboratory after 48 hours of exposure, as well as the monocomponent bait Mukhnet I (ivermectin 0.6%) and Mukhnet F (fipronil 0.15%) and Agita comparison drug (thiamethoxam 10%). The insecticidal efficacy of the developed bait Mukhnet IF against flies in the production environment on the first day after processing the livestock building was 96.7%, which is comparable to the efficiency of the monocomponent bait Mukhnet I and Mukhnet F and the comparison preparation. Obtained results allowed authors to propose «Method for reducing the number of flies at objects of veterinary sanitary inspection» (RU 2692620).
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