Input of comorbidities to hospitalization of patients with COVID-19

Abstract

<b>Introduction:</b> The number of patients with COVID-19 is increasing rapidly, but the relationship between comorbidity and hospitalization of patients with COVID-19 is still not clearly defined. <b>Aim:</b> To analyze the structure of comorbidity of patients with COVID-19 and its impact on hospitalization. <b>Methods:</b> The analysis of monitoring data of patients with COVID-19 with various comorbidities was carried out in the period from March to November 2020 in the Russian Federation. <b>Results:</b> A total of 90077 patients with comorbidities were identified among patients with COVID-19. Diseases of the cardiovascular system accounted for 50.54% (45713), diseases of the bronchopulmonary system - 14.14% (12791), diseases of the endocrine system - 9.26% (8375), oncology - 4.59% (4151), other diseases 21.47% (19047). Hospitalization of patients with the following comorbidities dominated: diseases of the cardiovascular system - 65.5% (OR 1.36; 95% CI 1.32-1.40), the endocrine system - 57.3% (OR 0.83; 95 % CI 0.79-0.87), bronchopulmonary system - 56.6% (OR 0.79; 95% CI 0.76-0.82), oncological diseases - 54.0% (OR 0.72; 95 % CI 0.68-0.77). The presence of bronchopulmonary diseases in patients did not increase the chances of hospitalization of patients with COVID-19. The frequency of hospitalization of patients with diseases of the cardiovascular system was significantly higher (p &lt;0.001) in comparison with other comorbidities. Their chances of being admitted to hospital increased 1.36 times compared to patients without such diseases. <b>Conclusions:</b> Patients with cardiovascular pathology had the highest risk of hospitalization. It is necessary to pay special attention&nbsp;to patients with concomitant cardiovascular&nbsp;pathology at the outpatient stage.