Abstract

Coronavirus disease 2019 (COVID-19) has had a devastating impact globally, with severe health and economic consequences. To prepare health systems to deal with the pandemic, epidemiological and cost projection models are required to inform budgets and efficient allocation of resources. This study estimates daily inpatient care costs of COVID-19 in South Africa, an important input into cost projection and economic evaluation models. We adopted a micro-costing approach, which involved the identification, measurement and valuation of resources used in the clinical management of COVID-19. We considered only direct medical costs for an episode of hospitalisation from the South African public health system perspective. Resource quantities and unit costs were obtained from various sources. Inpatient costs per patient day was estimated for consumables, capital equipment and human resources for three levels of inpatient care - general wards, high care wards and intensive care units (ICUs). Average daily costs per patient increased with the level of care. The highest average daily cost was estimated for ICU admissions - 271 USD to 306 USD (financial costs) and ~800 USD to 830 USD (economic costs, excluding facility fee) depending on the need for invasive vs. non-invasive ventilation (NIV). Conversely, the lowest cost was estimated for general ward-based care - 62 USD to 79 USD (financial costs) and 119 USD to 278 USD (economic costs, excluding facility fees) depending on the need for supplemental oxygen. In high care wards, total cost was estimated at 156 USD, financial costs and 277 USD, economic costs (excluding facility fees). Probabilistic sensitivity analyses suggest our costs estimates are robust to uncertainty in cost inputs. Our estimates of inpatient costs are useful for informing budgeting and planning processes and cost-effectiveness analysis in the South African context. However, these estimates can be adapted to inform policy decisions in other context.

Highlights

  • Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first discovered in December 2019 following an outbreak in the Hubei province of China

  • Inpatient costs per patient day were estimated for three broad cost categories and for three different levels of care – care provided within general wards, high care wards and care provided within intensive care units (ICUs)

  • Due to the longer length of stay in ICU with invasive mechanical ventilation (IMV), consumables that were required only once during a hospital episode had a lower daily cost, resulting in a lower overall cost of consumables compared to inpatient care requiring continuous positive airway pressure (CPAP) or non-invasive ventilation (NIV) in ICUs

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Summary

Introduction

Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first discovered in December 2019 following an outbreak in the Hubei province of China. By the beginning of March 2020, it had spread to several countries globally and on 11th March was declared a pandemic by the World Health Organization (WHO).[1] COVID-19 has since had a devastating impact globally, with severe health and economic consequences on individuals and households.[2]. Edoka et al and critical cases,[3] a nationwide lockdown was initiated on March 24, 2020 for approximately three months. During this period, a national COVID-19 costing working group was convened to support the National Department of Health (NDOH) in estimating a budget to prepare the public health system’s response to the pandemic. This study estimates inpatient care for managing COVID-19 patients in South Africa’s public hospitals, an important input into the national COVID-19 budget model

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