Abstract

Two cDNAs encoding inositol 1,4,5-trisphosphate (IP 3) receptors were amplified from rat olfactory tissue, and both exhibited 100% sequence identity to the short (Segment II−) variant of type I IP 3 receptor. Type III IP 3 receptor was also expressed in olfactory tissue. The distribution of IP 3 receptors included the olfactory epithelium, lamina propria, and glandular tissue. These results demonstrate the co-expression of multiple IP 3 receptor subtypes in olfactory cells, and suggest multiple functions for IP 3 receptors in this tissue.

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