Abstract

Abstract Inorganic–organic hybrid material catalyzed one-pot three-component Mannich reaction of ketones with aromatic aldehydes and different amines at ambient temperatures afforded β-amino carbonyl compounds in excellent yields. This method provides a novel and improved modification of three-component Mannich reaction in terms of mild reaction conditions and clean reaction profiles, using small amount of catalyst, simple workup procedure and ease of recovery and reusability of catalyst.

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