Abstract

Calves were immunized with non-irradiated and 20-KR-irradiated invective Dictyocaulus filaria larvae, or with non-irradiated and 5-KR-irradiated fifth-stage worms of the same parasite, given in two doses in 4 weeks apart. They developed partial resistance to the subsequent challenge with infective larvae of Dictyocaulus viviparus, as compared with non-immunized animals. Better protection was obtained in calves immunized with two doses of non-irradiated infective larvae than in those given two doses of 20-KR-irradiated infective larvae, non-irradiated fifth-stage worms, or 5-KR-irradiated fifth-stage worms. Moreover, the resistance exhibited by calves immunized with two doses of 10, 000 non-irradiated infective larvae each was higller in degree than that seen in those immunized with two do, ses of 5, 000. notn-irradiated infective larvae. The results obtained were evaluated on the basis of the fecal larval count, the number of worms recovered from the lungs, and the necropsy findings for the lungs.

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