Abstract
The need for innovative new solutions in diabetes therapy is obvious fromthe increasing prevalence of the disease, the associated morbid and health-economic consequences, and the fact that most patients are in poor glycaemic control, even when treatedwith insulin. Our growing understanding of diabetes and metabolism is, however, beginningto yield novel, promising therapies. In addition, exogenous insulin therapy is itself being refined, as exemplified by the improved pharmacokinetic properties of insulin analogues. Further improvement in treatment success is likely to be achieved by research aimed atan understanding of how best to individualize therapy and to increase doctors and patients' compliance.
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