Abstract

Neurostimulation devices, also referred to as neuromodulation devices, have ushered in a transformative era in medical treatment by utilizing electrical impulses to activate specific nerves or brain regions. These devices hold significant promise as therapeutic interventions for a range of medical conditions, encompassing chronic pain, Parkinson's disease, epilepsy, depression, and more. This paper presents a comprehensive review of neurostimulation devices, encompassing their historical evolution, underlying mechanisms, and diverse applications are spanning various medical domains. In particular, the paper delves into the progress achieved in spinal cord stimulators, deep brain stimulators, Vagus nerve stimulators, peripheral nerve stimulators, and transcutaneous electrical nerve stimulators (TENS). The discussion encompasses their clinical efficacy, advantages, and constraints, while also addressing the safety and ethical considerations associated with their implantation.

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