Innovations in Management of Complications

Abstract

Boston Keratoprosthesis (K-Pro) type 1 is the most widely used artificial cornea. K-Pro eyes require life-long follow-up by a multidisciplinary team involving a corneal specialist, a glaucoma specialist, and a retinal specialist. A deep understanding of potential complications and how to manage them is the key in achieving good outcomes. Complications may be related to the K-Pro itself or to other comorbidities frequently encountered in such complex eyes. The introduction of accurate protocols for preoperative planning, surgical technique, and postoperative follow-up has resulted in improved outcomes. Specifically, endophthalmitis prophylaxis and intraocular pressure management are some of the key aspects. This review constitutes a comprehensive overview of the most significant complications through the eyes of cornea, glaucoma, and retinal specialists with extensive experience in K-Pro surgery. The extensive preclinical and clinical research on Boston K-Pro 1 has shed light on the potential complications and their adequate prevention and management. Patients should be informed of the benefits and risks of the procedure, and the need of close follow-up throughout life.