Abstract
control 1677 + 178) or occipital (HD 858 2 302; control 987 t IS?) cortlces. The change in IP3 binding identified in HD brain here may reflect processes that alter receptor-activated IP3 formation or endoplasmic reticulum IP1 receptor sites and which are associated with or antecedent to neuronal cell death and loss. (P.P. Li is an OMHF Research Fellow and S.J. Kish an Ontario Career Scientist: supported in part by the MRC)
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