Abstract
Preimplantation genetic testing for aneuploidy (PGT-A) by next generation sequencing (NGS) has improved sensibility for the embryo’s ploidy report, however provides some diagnostic of uncertain clinical significance, such as mosaicism. Clinical management and ranking of mosaic embryos remain a challenge for providers. There is still lack of knowledge if other parameters could help to identify and better classify mosaic embryos. Since embryo morphology grade is routinely used for embryo selection, the aim of this study was to assess if there are differences in the morphology grade of inner cell mass (ICM) and trophoectoderm (TE) in blastocysts reported as low or high mosaics, comparing to the grading of euploid and aneuploid embryos.
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