Abstract
Combining N-heterocyclic carbenes with gold nanoparticles provides an ultrabright and fragment-free ionization platform for laser-desorption mass spectrometry. In their Research Article (e202219182), David M. Jenkins, Jon P. Camden et al. show that NHC functionalized nanoparticles can “give gold wings” in the mass spectrometer, enabling next generation applications of mass barcoding, data storage, and bioconjugation reaction monitoring.
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