Initial Surface Temperature of PMMA Plates Used for Daily Laser Calibration Affects the Predictability of Corneal Refractive Surgery

Abstract

To investigate the relevance of initial temperature of the polymethylmethacrylate (PMMA) plates used as a target for photoablation during calibration of excimer lasers performed in daily clinical routine. An experimental argon fluoride excimer laser with a repetition rate of 1050 Hz, a radiant exposure of 500 mJ/cm², and single pulse energy of 2.1 mJ was used for photoablation of PMMA plates. The initial plate temperature varied from 10.1°C to 75.7°C. The initial temperature was measured with an infrared camera and the central ablation depth of a myopic ablation of -9.00 diopters (D) with an optical zone of 6.5 mm was measured by means of a surface profiling system. The ablation depth increased linearly from 73.9 to 96.3 μm within a temperature increase from 10.1°C to 75.7°C (increase rate of 0.3192 μm/K). The linear correlation was found to be significant (P<.05) with a coefficient of determination of R²=0.95. Based on these results and assuming a standard room temperature of 20°C, optimal plate temperature was calculated to be 15°C to 25°C to maintain an ablation within 0.25 D. The temperature of PMMA plates for clinical laser calibration should be controlled ideally within a range of approximately ±5°C, to avoid visually significant refractive error due to calibration error. Further experimental investigations are required to determine the influence of different initial corneal temperatures on the refractive outcome.