Abstract
Objective: Several studies have evaluated the efficacy of continuous infusion of dexmedetomidine for procedural sedation of pediatric patients. There are few published reports of single dose dexmedetomidine for pediatric procedural sedation. We want to report on three pediatric patients who received single dose dexmedetomidine for procedural sedation. Methods: Case reports of pediatric patients who received intravenous dexmedetomidine for procedural sedation at Kentucky Children's Hospital. Results: Dexmedetomidine was administered as a single dose bolus of 1-3 mcg/kg over 10-15 minutes. In the clinical scenarios, effective sedation was achieved in order to perform MRI examinations and/or lumbar punctures. The only side effect related to administration was hypotension, which did not require intervention. Conclusion: Single dose dexmedetomidine appears to provide adequate procedural sedation for pediatric patients. Further studies are needed to confirm the effectiveness of this sedation regimen.
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