Abstract
Lumpectomy cavity radiotherapy boost after breast conserving surgery and whole breast irradiation reduces local cancer recurrence. This boost is typically delivered with external beam photons or electrons, encompassing the postoperative surgical cavity and a surrounding margin of normal breast tissue. External beam radiotherapy boost correlates with increased rates of breast fibrosis and may impair cosmetic outcomes. Multicatheter breast brachytherapy (MCBB) is an approach to deliver dose-escalated high dose rate radiation to the lumpectomy cavity while limiting additional radiation exposure to normal breast tissue and adjacent organs. This study evaluates the feasibility of using a multicatheter brachytherapy approach for cavity boost when combined with whole breast external beam radiotherapy.
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