Abstract
Research on bioprospecting bioactive secondary metabolites from marine bacteria has rapidly expanded in the past few decades. The complexity of the environment in which bacterial communities live involves complex interactions with other communities competing for resources for survival. Previously, the ability of Pseudovibrio denitrificans has been demonstrated to inhibit the growth and virulence of different pathogens such as Vibrio parahaemolyticus. The antagonism of these bacteria has been studied, considering the latter's importance in producing farmed shrimp. The molecules produced by P. denitrificans may be fundamental for its antibacterial effect. In the present work, we examine LC/MS profiles of the interaction under two different circumstances: direct and delayed antagonism. The results show marked differences in the chemical composition between both interactions and the tentative identification of antibacterial and antibiofilm compounds. The observed profile could be part of P. denitrificans chemical arsenal to halt V. parahaemolyticus growing. The presented data is relevant to designing future studies on bacterial antagonism with relevant implications for the aquaculture industry. Keywords: vibriosis, probiotics, chemometrics, white shrimp.
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