Abstract
Weak acid and neutral fractions separated from the extracts of male and female human urine showed an inhibitory action against contraction of smooth muscle preparations. Their inhibitory action was tested on contraction of isolated guinea-pig ileum induced by histamine and isolated rat uterus by oxytocin. It was suggested that one of the principles of inhibitory activity in the urine might be the metabolites of steroid hormones.
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More From: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
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