Abstract
AIM: the present study is aimed to investigate the standardized aqueous extract of Euphorbia prostrate (EPA) for its anti-inflammatory/anti-arthritic potential. METHODS: EPA was standardized by HPLC on the basis of quercetin, quercetrin, rutin and luteolin glucoside as markers. EPA was evaluated by in vivo (against carrageenan induced inflammation and Mycobacterium adjuvant induced chronic inflammtion) and in vitro (LPS induced iNO’s measurement) methods of anti inflammatory activity. Antioxidant activity of EPA was determined by DPPH assay. Acute toxicity/ safety and MLD50 was calculated in mice. RESULTS: Results of in vivo and in vitro studies employing rodents and J774 cell lines respectively, revealed it to possess highly significant anti-inflammatory/ anti-arthritic activity. Furthermore, γ-Glutamyle transpeptidase (γ-GT) values were significantly (P
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Spatula DD - Peer Reviewed Journal on Complementary Medicine and Drug Discovery
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
