Abstract
Cortical circuits transform neural information within a stereotyped laminar architecture. These operations require the coordinated activity of excitatory and inhibitory neurons. Inhibitory GABAergic interneurons are a minority of all cortical neurons but can be crucially important in regulating spatiotemporal dynamics of both local and global circuit activities. In this lecture, I will tell our studies of functional organization and laminar interactions in cortical circuits using newly developed optical mapping tools and novel genetic methods for cell‐type specific manipulation. I will talk about our new observation that excitatory and inhibitory cortical connections are spatially and functionally balanced, and discuss how this new information is related to specific inhibitory neuronal control of a critical period of brain plasticity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
