Abstract
Antimutagenic potential of Cuminum cyminum seed oil was evaluated using modified bacterial reverse mutation assay. Salmonella typhimurium strains were used for antimutagenic evaluation with pre-, co-, and post-treatment methods with prior cytotoxicity and mutagenicity evaluation. C. cyminum oil produced cytotoxicity in S. typhimurium strains at concentrations ranging from 0.08 to 2.50 and 0.31 to 2.50 μL/plate in the absence and presence of metabolic activation, respectively. C. cyminum was non-mutagenic and exhibited a different range of antimutagenic potential in all the S. typhimurium strains at non-cytotoxic concentrations.
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