Abstract
The purpose of this study was to determine whether unripe plantain products has hypoglycemic properties by comparing its potency with commercial drug (arcabose) on key enzymes linked to diabetes (α‐amylase and α‐glucosidase) and hypertension [(Angiotensin‐I Converting Enzyme) (ACE)]Diabetes was induced by combined feeding of the adult male Wistar rats with High fat diet (Lard) plus intraperitoneal injection of streptozotocin (25 mg/kg body weight). After sacrifice, the pancreas was examined for α‐amylase, α‐glucosidase angiotensin‐1 converting enzyme. The plasma obtained was also studied by testing for GST, GSH and Malonadialdehyde (MDA) activities. The diabetic rats showed elevated (P<0.05) levels of α‐amylase, α‐glucosidase and ACE and MDA (end product of lipid peroxidation). However, the effect of treatment of unripe plantain products supplement diets on diabetic rats (after 30 days) was significantly (P<0.05) reversing the above mentioned parameters toward normalcy.These results imply that there is more to unripe plantain than mere consumption. It also brings about a new dimension to the management of diabetes and its attendant complications.
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