Abstract
THE induced biosynthesis of many microbial enzymes is susceptible to the inhibitory effect of glucose1. The physiological significance of this phenomenon has been indicated by the study of an L-histidine-requiring mutant strain of Aerobacter aerogenes in which glucose inhibits the formation of histidase, thereby conserving the L-histidine for its specific role as growth factor2. Under conditions that permit a gratuitous, linear production of myoinositol dehydrogenase (another inducible enzyme in A. aerogenes) in the absence of the inducing agent, the glucose effect is still operative, indicating that glucose interferes with the production of enzyme rather than with .the process of induction3.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
