Abstract
Cycloheximide administered to rats in non-toxic doses immediately after pyloric ligation results in a lower incidence of experimental gastric ulcers. The effect is paralleled by an impaired secretion of hydrochloric acid (more than 90 per cent inhibition). Simultaneously the activity of pepsin in gastric juice and in homogenates of gastric mucosa was reduced by 60 per cent and mucoproteins were lowered by 30 per cent. The basal and pentagastrin-stimulated secretion were inhibited by cycloheximide to the same extent.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
