Abstract
The effects of 4-h incubation in the presence of bombesin on the incorporation of [ 3H]-thymidine into DNA of the rat thyroid lobes, collected from animals treated in vivo with a long-acting somatostatin analog (SMS 201–995) or with 0.9% NaCl, were investigated. It was shown that not only in vivo injections of SMS 201–995, but also, unexpectedly, in vitro incubation with bombesin inhibited [ 3H]-thymidine incorporation. The two examined substances did not reveal any additive action in their inhibitory effects on the thyroid growth.
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