Abstract
PTP1B tyrosine phosphatase is involved in the development of many types of cancers, such as breast cancer or lung cancer. Therefore, PTP1B is a promising target for anticancer therapy. The purpose of this review was to present the studies on selected PTP1B inhibitors as a possible treatment and describe the latest trends of current research in this field. This literature review was performed using the PubMed database and the analysis of previous research studies of our Department. Recent studies have shown that PTP1B, due to its implication in oncogenic transformation, represents a promising drug target. The selected compounds that are effective PTP1B inhibitors can be considered a promising anticancer treatment, both as monotherapy and in combination with other anticancer drugs.
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