Abstract
SummaryWhen traumatization of one horn of the uterus of progesterone-treated ovariectomized mice was delayed until 4 days after the traumatization of the contralateral horn, deciduomata developed only in the horn first stimulated. On the other hand, deciduomata developed in both horns when the uterus was traumatized bilaterally during a single operation. Since the deciduomal reaction is the experimental equivalent of the maternal placenta, these observations suggest that the maternal placenta plays an important role in the desensitization of the pregnant uterus to decidua formation. This is an important factor in the prevention of superfetation.
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