Abstract
ObjectivesPoly (ADP-ribose) polymerase (PARP) played an important role in the pathogenesis of heart ischaemia/reperfusion (I/R) injury. The mechanisms are still not thoroughly understood. Here we investigated the effect of PARP...
Highlights
Objectives(ADP-ribose) polymerase (PARP) played an important role in the pathogenesis of heart ischaemia/reperfusion (I/R) injury
We investigated the effect of PARP inhibition on heart I/R injury and elucidated the underlying mechanisms
Administration of DPQ decreased myocardial infarction size from 60.97±4.22% to 39.03±3.94% p
Summary
(ADP-ribose) polymerase (PARP) played an important role in the pathogenesis of heart ischaemia/reperfusion (I/R) injury. The mechanisms are still not thoroughly understood. We investigated the effect of PARP inhibition on heart I/R injury and elucidated the underlying mechanisms
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