Abstract

Oolong tea extract (OTE) was found to inhibit sucrase from the small intestine and α-amylase. The IC50 values were 0.25 mg/mL and 5.0 mg/mL respectively. The effect of OTE on postprandial hyperglycaemia was investigated in vivo in rats loaded with sucrose, maltose, soluble starch or glucose. OTE suppressed the increase of blood glucose levels in sucrose-, maltose- and glucose-loaded rats, but not in soluble starch-loaded rats. From these results it was assumed that orally administered OTE inhibits intestinal glycosidases, especially sucrase, thereby deterring the digestion of certain amounts of sucrose or maltose, and also inhibits glucose absorption partially, leading eventually to a reduction in blood glucose levels.

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