Inhibition of Phosphotidylcholine Liposome Oxidation by Phenolics from Aloe Extracts: A. arborescens, A. pillansii, and A. squarrosa

Abstract

Various species from the genus Aloe, which there are more than 500 in the world, are considered to be important sources of biologically active compounds, and their numerous biological qualities are attracting research interest. Of Aloe species, A. arborescens and A. vera are the most studied and used; however, some other species from this genus exhibit no less biological activity, in particular, antioxidant activity, than these two. In this work, the antioxidant activity of extracts obtained from A. аrborescens, A. pillansii, and A. squarrosa leaves is evaluated and compared using the model of initiated oxidation of phosphotidylcholine liposomes, and their total phenolic content is determined. The antioxidant activity of A. pillansii extract was ~12 and 4 times greater than that of A. arborescens and A. squarrosa, respectively. However, the difference in the total phenolic content of these extracts is not so large, suggesting that A. pillansii leaves may have a more complex antioxidant profile and a higher concentration of active phenolic metabolites than does A. arborescens. The findings of this study inspire further research into the biological activity of A. pillansii.