Abstract
TRIPLOIDY—the possession of three instead of two sets of chromosomes per cell-is a substantial cause of death in man. At least 1% of conceptions produce triploid zygotes, most of which are aborted by the end of the third month of pregnancy1. Only a few triploid infants are reported to have survived birth but the reason is not known. Death in utero also seems to be the fate of triploid rats, mice and rabbits2, but in amphibia3, Drosophila4 and many plants5,6, triploid individuals are not only viable but do not differ markedly from normal diploids.
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