Abstract
The crude chloroform bark extract of an undescribed species of Salacia from Monteverde, Costa Rica, showed cruzain inhibitory activity (IC50= 11.4 ± 0.6 μg/mL). Activity-directed chromatographic separation led to isolation of four active friedelane triterpenoids, 25,28-dihydroxyfriedelin, canophyllol, tingenone, and the novel 29-hydroxyfriedelan-3-on-28-al.
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